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Symbol
Name
ID

Pgm3
phosphoglucomutase 3
MGI:97566

Phenotype annotations related to immune system

Darker colors indicate more annotations

Human Phenotypes

Reduced antigen-specific T cell proliferation

Increased circulating IgA level

Increased circulating IgE level

Increased circulating IgG level

Increased circulating IgM level

Eosinophilia

Neutropenia

Neutropenia in presence of anti-neutropil antibodies

Abnormal CD4:CD8 ratio

Decreased proportion of CD4-positive helper T cells

Abnormal proportion of CD8-positive T cells

Decreased proportion of CD3-positive T cells

T lymphocytopenia

Lymphopenia

Leukopenia

Reduced natural killer cell count

Chronic sinusitis

Allergic rhinitis

Persistent EBV viremia

Esophagitis

Chronic otitis media

Membranoproliferative glomerulonephritis

Abscess

Cutaneous abscess

Eczematoid dermatitis

Atopic dermatitis

Recurrent skin infections

Chronic mucocutaneous candidiasis

Osteomyelitis

Recurrent pneumonia

Autoimmunity

Rheumatoid factor positive

Immunodeficiency

Severe combined immunodeficiency

Drug allergy

Food allergy

Asthma

Sepsis

Recurrent infections

Recurrent bacterial infections

Recurrent staphylococcal infections

Recurrent Staphylococcus aureus infections

Recurrent fungal infections

Recurrent respiratory infections

Recurrent viral infections

Severe varicella zoster infection

Molluscum contagiosum

Disease(s) Associated with PGM3

immunodeficiency 23

Mouse Phenotypes		increased spleen weight	increased pro-B cell number	abnormal T cell differentiation	abnormal thrombopoiesis	absent follicular B cells	decreased B cell number	decreased T cell number	decreased leukocyte cell number	increased spleen red pulp amount	glomerulonephritis
Availability	Mouse Genotype	increased spleen weight	increased pro-B cell number	abnormal T cell differentiation	abnormal thrombopoiesis	absent follicular B cells	decreased B cell number	decreased T cell number	decreased leukocyte cell number	increased spleen red pulp amount	glomerulonephritis
	Pgm3^mld1/Pgm3^mld1
	Pgm3^{Gt(W037B08)Wrst}/Pgm3^mld1

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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